Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce is a delightful dish that combines savory Cajun-seasoned chicken, tender rotini pasta, and a creamy mozzarella garlic butter sauce. Perfect for family dinners or gatherings, this recipe stands out for its delicious flavors and quick preparation. Your taste buds will thank you as the rich sauce envelops every bite of pasta and chicken.
Why You’ll Love This Recipe
- Quick to Prepare: In just 35 minutes, you can create a hearty meal that satisfies everyone at the table.
- Flavor Explosion: The blend of Cajun seasoning with garlic and creamy cheeses delivers an irresistible taste.
- Versatile Dish: Great for weeknight dinners or special occasions; it adapts to any setting.
- One-Pan Wonder: Minimal cleanup required since everything cooks in one skillet.
- Customizable: Adjust the spice level to your preference or throw in extra veggies for added nutrition.

Tools and Preparation
To make preparing this Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce easier, gather your essential tools beforehand. Having everything ready ensures a smooth cooking process.
Essential Tools and Equipment
- Large pot
- Skillet
- Colander
- Measuring cups and spoons
- Wooden spoon or spatula
Importance of Each Tool
- Large pot: This is essential for boiling the rotini pasta evenly without crowding.
- Skillet: A good quality skillet allows for even cooking of the chicken and provides enough space to mix in the sauce.
- Colander: This tool lets you easily drain the cooked pasta while retaining the starch-filled water for later use.
Ingredients
For the Chicken
- 1 lbs boneless, skinless chicken breasts, cut into bite-sized pieces
- 1 tsp Cajun seasoning, adjust to taste
- Salt and black pepper, to taste
For the Pasta
- 12 oz rotini pasta
For the Sauce
- 2 tbsp olive oil
- 3 tbsp unsalted butter, divided
- 4 cloves garlic, minced
- 1 cups heavy cream
- 1 cups shredded mozzarella cheese
- ½ cup freshly grated Parmesan cheese
- 1 tsp Italian seasoning
- Crushed red pepper flakes, to taste
For Garnish
- Fresh chopped parsley, for garnish
How to Make Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
Step 1: Boil the Pasta
Boil a large pot of salted water. Add the rotini and cook until al dente, about 9–10 minutes. Reserve ½ cup of the pasta water, then drain and set aside.
Step 2: Season the Chicken
Season the chicken pieces with Cajun seasoning, salt, and black pepper. Toss until evenly coated.
Step 3: Cook the Chicken
Heat olive oil and 1 tablespoon of butter in a large skillet over medium-high heat. Add the chicken and sear for 7–8 minutes until golden and cooked through, stirring occasionally. In the last minute, stir in half of the minced garlic to infuse flavor. Remove chicken from skillet and set aside.
Step 4: Sauté Garlic
Lower heat to medium. Add remaining 2 tablespoons of butter to the same skillet, followed by the rest of the garlic. Sauté for 30 seconds until fragrant.
Step 5: Make The Cream Sauce
Pour in heavy cream while stirring as it heats. Let simmer for 2–3 minutes to thicken slightly.
Step 6: Add Cheeses
Stir in mozzarella and Parmesan cheeses. Mix well until melted into a thick, velvety sauce.
Step 7: Season The Sauce
Season with Italian seasoning, crushed red pepper flakes (if using), plus additional salt and pepper to taste.
Step 8: Combine Pasta
Add cooked rotini to the skillet and toss until all spirals are coated with that creamy Cajun cheese sauce. If needed, add a splash of reserved pasta water to loosen up the sauce.
Step 9: Serve
Serve your cheesy Cajun Chicken Rotini hot, garnished with fresh parsley and extra cheese if desired. Enjoy!
How to Serve Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce is a rich and flavorful dish that brings a taste of the South to your table. This creamy pasta is not only delicious on its own but can be served in various delightful ways to enhance your dining experience.
Pair with a Fresh Salad
- Mixed Greens Salad: A simple salad with mixed greens, cherry tomatoes, and a light vinaigrette complements the richness of the rotini.
- Caesar Salad: The classic Caesar salad adds a crunchy texture that balances the creamy sauce.
Add Some Garlic Bread
- Toasted French Bread: Slice a baguette, spread garlic butter, and toast until golden for an irresistible side.
- Cheesy Garlic Knots: These soft, cheesy bites are perfect for dipping into the sauce.
Serve with Wine
- White Wine: A chilled glass of Chardonnay pairs beautifully with the creamy flavors.
- Red Wine: A light Pinot Noir enhances the Cajun spices without overwhelming the dish.
Garnish with Fresh Herbs
- Chopped Parsley: Sprinkle fresh parsley over the top for a pop of color and freshness.
- Basil Leaves: Fresh basil adds an aromatic touch that elevates the dish’s overall flavor profile.
How to Perfect Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
To achieve the best results when making this delectable dish, follow these simple tips. They will help you create a creamy and perfectly seasoned sauce that everyone will love.
- Use Fresh Ingredients: Fresh garlic and herbs elevate the flavors significantly compared to dried options.
- Adjust Cajun Seasoning: Taste as you go; add more seasoning if you prefer extra heat or depth in flavor.
- Cook Pasta Al Dente: To avoid mushy pasta, cook it slightly less than package instructions suggest for perfect texture.
- Reserve Pasta Water: The starchy pasta water helps adjust sauce consistency; add it gradually until desired thickness is reached.
- Let Sauce Simmer: Allowing the sauce to simmer helps develop flavors and thicken it nicely before adding cheese.
Best Side Dishes for Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
Complement your Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce by serving it alongside these tasty side dishes. Each option provides balanced flavors that enhance your meal.
- Garlic Roasted Broccoli: Tender broccoli florets roasted with garlic bring a nutritious crunch to your plate.
- Corn on the Cob: Sweet corn brushed with butter is a classic side that pairs well with rich pasta dishes.
- Coleslaw: A tangy coleslaw offers a refreshing contrast to the creamy rotini and adds some crunch.
- Vegetable Medley: Sautéed seasonal vegetables provide color and nutrition while keeping the focus on your main dish.
- Fried Green Tomatoes: Crispy fried green tomatoes add Southern flair and pair wonderfully with Cajun flavors.
- Potato Wedges: Seasoned potato wedges are great for soaking up any leftover sauce on your plate.
Common Mistakes to Avoid
When making Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce, it’s easy to make mistakes that can affect the dish’s flavor and texture. Here are some common pitfalls to avoid.
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Not seasoning the pasta water: Failing to salt the water while cooking the rotini can lead to bland pasta. Always use enough salt in the boiling water for flavorful results.
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Overcooking the chicken: Cooking chicken for too long can dry it out. Aim for a golden sear and ensure it’s cooked through but still juicy by monitoring cooking time closely.
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Skipping the reserved pasta water: Discarding the pasta water means missing out on a key ingredient that helps adjust the sauce’s consistency. Always save some before draining your pasta.
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Using cold ingredients: Adding cold cream or cheese can shock the sauce and prevent smooth melting. Let these ingredients come to room temperature before use.
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Adding all spices at once: Introducing all spices simultaneously can overwhelm your dish. Gradually add seasonings and taste as you go for balanced flavors.

Storage & Reheating Instructions
Refrigerator Storage
- Store in an airtight container.
- Keep in the fridge for up to 3 days.
Freezing Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
- Freeze in a freezer-safe container.
- Can be stored for up to 2 months.
Reheating Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
- Oven: Preheat to 350°F (175°C) and heat covered for about 20 minutes until warmed through.
- Microwave: Heat in short intervals, stirring frequently, until hot.
- Stovetop: Warm over low heat, adding a splash of milk or reserved pasta water for moisture.
Frequently Asked Questions
Here are some questions readers often have about Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce.
What is Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce?
Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce is a creamy pasta dish featuring rotini noodles tossed with seasoned chicken in a rich garlic butter sauce, enhanced with mozzarella cheese.
Can I customize the spice level?
Yes! You can adjust the Cajun seasoning according to your preference. Add more for extra heat or reduce it if you prefer milder flavors.
How do I make this dish vegetarian?
For a vegetarian version of Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce, substitute chicken with mushrooms or bell peppers and use vegetable broth instead of chicken broth if desired.
Can I use another type of cheese?
Definitely! While mozzarella adds creaminess, you can experiment with other cheeses like cheddar or gouda for different flavors in your sauce.
Final Thoughts
Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce is not only delicious but also versatile. Feel free to customize it by adding vegetables or adjusting spices according to your taste. This comforting dish is perfect for family dinners or gatherings, so give it a try!
Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce
Cajun Chicken Rotini with Mozzarella Garlic Butter Sauce is a mouthwatering dish that brings together the bold flavors of Cajun-seasoned chicken, al dente rotini pasta, and a creamy garlic butter sauce infused with mozzarella. Perfect for family dinners or gatherings, this dish is not only quick to prepare (ready in just 35 minutes), but it also delivers a delightful explosion of taste that will have everyone asking for seconds. The one-pan cooking method makes cleanup a breeze, while the option to customize spice levels and add vegetables ensures that every plate can be tailored to your preference. Indulge in this comforting, savory meal that’s sure to impress!
- Prep Time: 10 minutes
- Cook Time: 25 minutes
- Total Time: 35 minutes
- Yield: Serves 4
- Category: Dinner
- Method: One-Pan Cooking
- Cuisine: Cajun
Ingredients
- 1 lb boneless, skinless chicken breasts
- 12 oz rotini pasta
- 2 tbsp olive oil
- 3 tbsp unsalted butter
- 4 cloves garlic
- 1 cup heavy cream
- 1 cup shredded mozzarella cheese
- ½ cup grated Parmesan cheese
- Cajun seasoning, salt, black pepper, Italian seasoning
Instructions
- Boil salted water in a large pot and cook rotini until al dente; reserve pasta water.
- Season chicken with Cajun seasoning, salt, and pepper.
- Heat olive oil and 1 tbsp butter in a skillet; cook chicken until golden (7–8 minutes).
- Sauté garlic in remaining butter until fragrant.
- Stir in heavy cream; let simmer for 2–3 minutes.
- Add cheeses; mix until melted into a thick sauce.
- Combine cooked rotini with sauce; use reserved pasta water as needed.
- Serve hot garnished with parsley.
Nutrition
- Serving Size: 1 plate (approximately 400g)
- Calories: 660
- Sugar: 3g
- Sodium: 850mg
- Fat: 39g
- Saturated Fat: 20g
- Unsaturated Fat: 17g
- Trans Fat: 0g
- Carbohydrates: 50g
- Fiber: 3g
- Protein: 30g
- Cholesterol: 120mg